I have been using XP x64 for the last few months:
I have not found a single game that won't play on XP x64.
The major hardware manufacturers make drivers for it... Though, as always, Creative's drivers suck ass.
There is NO reduction in performance (with AMD CPU's). In fact... Using an Athlon64, 32 bit FPU intensive apps running in compatibility mode will recieve a slight performance increase. However, Pentium 4's with EMT64 in this situation will actually lose performance.
Its FREE to try for 6 months.
[....]
If you do use it:
Say goodbye to NGO optimized drivers.
Say goodbye to your game port.
No software or drivers to connect TI calcs.
Creative's 64-bit drivers suck more than their 32-bit versions.
Can't install MOHAA on drive C: and many other small quirks with some older 32-bit games.
[....]
If you're going to buy a new copy of XP, then give XP x64 a try (
trial linky). If you already have a copy of XP that you can use, then don't bother.